免疫力與認知障礙症

認知障礙症和一般的衰老中,記憶力和認知能力都會受到影響。 隨著年齡的增長,大腦的體積縮小,尤其是額葉皮層。 在某些大腦區域中,神經元之間的交流會減少,尋找單詞和記憶的難度增加,亦難以同一時間處理多項事情,注意力和記憶力會逐漸下降。 

科學家提出一項關於免疫系統與大腦之間聯繫的有趣研究-當中探討免疫力如何具有預防認知障礙症的能力!

免疫反應是對抗認知障礙症的保護因素

  • 研究結果表明,患有認知障礙症的人會容易失去記憶力,且他們的其他認知技能速度也相對較慢,而造成這差異的原因是免疫反應。在一項名為“腦脊液中可溶性TREM2的增加與認知障礙症的認知下降和臨床下降相關的研究”中,研究人員發現,認知障礙症患者的認知能力下降相對較慢,原因是與他們具有較高水平的蛋白質有關,這些蛋白質能夠幫助免疫細胞清除大腦中的斑塊狀細胞碎片。這種蛋白質稱為TREM2,在整個免疫系統中都顯示出抵擋認知障礙症的強大能力。
  • TREM2蛋白主要由神經膠質細胞產生,神經膠質細胞是一種膠質細胞,是大腦和脊髓的主要免疫系統防線。這些免疫細胞有助於保持大腦健康,清除細胞碎片,包括斑塊狀澱粉樣β澱粉,這是認知障礙症的成因。
  • 進一步的研究發現,有認知障礙症並具有較高TREM2水平的患者,多年來顯示出其認知能力和海馬體體積的變化較少。海馬體是大腦的一部分,對學習和記憶至關重要。那些患有癡呆症但TREM2水平較高的人,其記憶力減退也較慢,並且從正常認知到患有認知陣礙症的早期體徵進展更為緩慢。

維持強大的免疫系統

  • 研究指出,增強免疫力、TREM2和神經膠質細胞的治療,或有效能夠減緩認知障礙症的惡化。 科學家正在研究何時和如何有效地增加TREM2

因此,當他們還在為此而努力時,您如何才能幫助自己建立強大的免疫系統? 以下是一些簡單的建議:

  • 避免吸煙,但適量的酒精能夠幫助強化免疫系統
  • 保持多吃水果和蔬菜的飲食習慣
  • 定期控制體重和加強運動
  • 確保優質的睡眠
  • 注意個人衛生和攝入適當的營養以增強免疫力,避免受到外來感染
  • 為了達到最大化的健康目標,可服用合適的健康補充劑,例如專注於免疫力系統的補充劑,或包含蝦青素、核苷酸、NAD+、或更多益處的補健品。 S-CELL提供有助免疫力-【好細胞免疫專方】

 

Immunity & Alzheimer

In both Alzheimer’s disease and aging in general, memory and cognitive skills are some of the affected areas due to these occurrences. The brain shrinks in volume with aging, particularly in the frontal cortex. In certain brain regions, communication between neurons can be reduced, there is increased difficulty in finding words and recalling something, problems with multi-tasking, mild decreases in concentration, and memory decline.

Research brings up an interesting and useful study on the linkage between the immune system and the brain - which specifically talks about how it has the ability to function as protection! 

Immune Response as a Protective Factor Against Alzheimer’s Disease

  • Some people with Alzheimer’s Disease lose memory and other cognitive skills slower than others, and findings say that immune responses are a part of why there is a difference. On a study titled Increased soluble TREM2 in cerebrospinal fluid is associated with reduced cognitive and clinical decline in Alzheimer's disease, researchers found out that the reason behind the slower loss of cognitive skills in people with AD is linked to them having higher levels of a protein that helps immune cells clear plaque-like cellular debris from the brain. This protein is called TREM2, which along the entire immune system shows a promising ability to help fight Alzheimer’s disease.
  • TREM2 proteins are primarily made by microglia, which is a type of glial cell that acts as the primary line of immune system defense for the brain and spinal cord. These scavenging immune cells help to keep the brain healthy, clears cellular debris, including the plaque-like amyloid-beta that is a hallmark of AD.
  • Further research found that individuals with AD and evidence of higher TREM2 levels have shown over the years less change in their cognitive abilities and in the volume of their hippocampus, which is a brain part that is vital for learning and memory. Those with dementia but with higher levels of TREM2 also showed a slower decline in memory and progressed more slowly from normal cognition to early signs of AD or full-blown dementia.

Maintaining a strong immune system

  • The studies suggest that treatments designed to boost immunity, or specifically TREM2 and the activation of microglia in the brain might hold its promising ability to slow the progression of Alzheimer’s Disease. Research is now ongoing on when and how to target TREM2.So while they’re on the hard work for it, how can you help yourself build a strong immune system? Here are recommended simple ways you can start off with:
  • Avoid smoking, and alcohol should be in moderate intake
  • Consume a diet high in fruits and vegetables
  • Manage your weight and exercise regularly
  • Get some proper sleep
  • Take steps to avoid infection such as proper hygiene and consuming the right nutrients for immunity.
  • For maximum health goals, also add in the right health supplements, such as those that focus on immunity revival, or those that contain Astaxanthin, Nucleotide, NAD+, and more benefits. Our health shop contains the supplements that match your immunity - Immune Revival!

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